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Closed-Loop Interrogation of Whole-Brain Activity

Polygon

Raymond Dunn Headshot

Raymond L. Dunn, PhD

Kato Lab, UC San Francisco


Dual-Colour Optical Interrogation of GABAergic Release in Mammalian Motor Control

OASIS Photometry

Shan Sohail Headshot

Muhammad Shan Sohail

Milosevic Lab, University of Toronto


Dual‐Wavelength Responsive Hydrogel Glue Enabled by Precise Mightex Light Control

LEDs

Huaming Wang Headshot

Huaming Wang, PhD

Zhang Lab, University of Pittsburgh


Studying Negative Affect Using a Head-Fixed Rodent Behavior Training System and Mightex Behavior Camera

OASIS Fiberscope

Suzy Xu Headshot

Suzy Xu

Creed Lab, Washington University in St. Louis


Head-Fixed Single-Cell Calcium Imaging of the Ventral Pallidum with OASIS Fiberscope

OASIS Fiberscope

LEDs

Justin Wang Headshot

Justin Wang

Kravitz Lab, Washington University in St. Louis


A Multiple Channel 2D Optical Interface to 3D Engineered Neural Cultures

Polygon

Saeed Omidi Headshot

Saeed Omidi

Berdichevsky Lab, Lehigh University


Optical Interrogation of cAMP Signaling in Behaving Animals Reveals cAMP-Dependent Neural Circuit Activity Underlying Hippocampus-Dependent Short-Term Learning and Memory

OASIS Fiberscope

Jayant Rai Headshot

Jayant Rai

Okamoto Lab, University of Toronto


Noradrenergic modulation of the prefrontal cortex is impaired in Grin2a mutant mice

Polygon

Hassan Hosseini Headshot

Hassan Hosseini

Jones Lab, University of Michigan


Synaptic Input Pattern Learning in CA1 Pyramidal Neurons of Mouse Hippocampus

Polygon

LEDs

Anzal KS Headshot

Anzal KS

Bhalla Lab, NCBS-TIFR


Biophysical effects of focused and defocused image stimuli on dopaminergic amacrine cells and AII amacrine cells in the mouse retina

Polygon

LEDs

So Chung Him Headshot

So Chung Him, PhD

Feng Lab, Hong Kong Polytechnic University


Relating cerebellar glutamatergic dysfunction and age effects on behavioral phenotype in Shank3△e4-22 mutant mice

Polygon

Rajaram Kshetri Headshot

Rajaram Kshetri

Richardson Lab, Southern Illinois University


Single-cell isolation using the optoelectronic microrobot

Polygon

LEDs

Mohamed Elsayed Headshot

Mohamed Elsayed, PhD

Wheeler Lab, University of Toronto


In-vitro seizure suppression by Patterned Optogenetic Stimulation while Allowing Information Processing in Hippocampus

Polygon

Joynal Abedin Headshot

Joynal Abedin, PhD

Berdichevsky Lab, Lehigh University


Reclusive Chandeliers: Dentate Axo-axonic Cells are Functionally Isolated Early After Status Epilepticus

Polygon

Archana Proddutur Headshot

Archana Proddutur, PhD

Santhakumar Lab, University of California Riverside


Optoelectronic tweezers based on patterned illumination for cell and micro-robotic manipulation

Polygon

Shuailong Zhang Headshot

Shuailong Zhang, PhD

Wheeler Lab, University of Toronto


Optogenetically Eliciting Precisely-Timed Action Potentials in Cerebellar Purkinje Cell Axons

Polygon

LEDs

Kim Gruver Headshot

Kim Gruver, PhD

Watt Lab, McGill University


Optogenetic induction of long-term potentiation at excitatory synapses onto hippocampal somatostatin interneurons and its regulatory effect on CA1 local circuit

Polygon

Azam Asgarihafshejani Headshot

Azam Asgarihafshejani, PhD

Lacaille Lab, University of Montreal


Spatial control of microtubule dynamics at the subcellular scale by patterned illumination

Polygon

Jeffrey van Haren Headshot

Jeffrey van Haren, PhD

Wittmann Lab, University of California San Francisco


Towards a microcircuit-based understanding of multiplexed spike code in the neocortex

Polygon

Matthew Tran Headshot

Matthew Tran, PhD

Richards Lab, University of Toronto


Activation of Somatostatin-Expressing Neurons in the Lateral Septum Improves Stress-Induced Depressive-like Behaviors in Mice

OASIS Fiberscope

Huanhuan Li Headshot

Huanhuan Li

Lau Lab, City University of Hong Kong


In Vivo Freely-Behaving Imaging of Intracellular Signalling Pathways of Hippocampus-Dependent Memory

OASIS Fiberscope

Jayant Rai Headshot

Jayant Rai

Okamoto Lab, University of Toronto


Multiple Brain Region Calcium Imaging Using OASIS Fiberscope

OASIS Fiberscope

Nick Frost Headshot

Nick Frost, Prof.

Frost Lab, University of Utah


Cortical Observation by Synchronous Multifocal Optical Sampling Reveals Widespread Population Encoding of Actions

Polygon

Isaac V. Kauvar Headshot

Isaac V. Kauvar, PhD

Deisseroth Lab, Stanford University


Differential Synaptic Input to External Globus Pallidus Neuronal Subpopulations In Vivo

LEDs

Maya Ketzef Headshot

Maya Ketzef

Silberberg Lab, Karolinska Institute


Activation of Somatostatin-Expressing Neurons in the Lateral Septum Improves Stress-Induced Depressive-like Behaviors in Mice

OASIS Fiberscope

Huanhuan Li Headshot

Huanhuan Li

Lau Lab, University of Hong Kong


Maintenance of cell type-specific connectivity and circuit function requires Tao kinase

LEDs

Frederico Marcello Headshot

Frederico Marcello Tenedini

Soba Lab, University Medical Center


Mutant -Synuclein Overexpression Induces Stressless Pacemaking in Vagal Motoneurons at Risk in Parkinson’s Disease

LEDs

Efrat Headshot

Efrat Lasser-Katz

Goldberg Lab, The Hebrew University of Jerusalem


Optogenetic characterization of muscular responses in the tibialis anterior (TA) muscle

OASIS Macro

Polygon

Emma Moravec Headshot

Emma Moravec, PhD

Williams Lab, Marquette University


Optogenetic stimulation of olfactory cortex to mimic odors

POLYGON

Pedro Headshot

Pedro Herrero-Vidal, PhD

Rinberg Lab, New York University


All-Optical Interface to a 3D Neuronal Construct Mimicking Cortical Pathway Connectivity

POLYGON

Saeed Omidi Headshot

Saeed Omidi

Berdichevsky Lab, Lehigh University


Light-sensitive Ca2+ Signaling in the Mammalian Choroid

POLYGON

Alex Headshot

Alex Aupetit

Gonzales Lab, University of Nevada


Grin2a Dysfunction Impairs Cognitive Flexibility by Disrupting LC Modulation of mPFC Circuits

POLYGON

Hassan Headshot

Hassan Hosseini

Jones Lab, University of Michigan


Deep model predictive control via optogenetics with the Mightex Polygon

POLYGON

Jean-Baptiste Lugagne, PhD

Dunlop Lab, Boston University


Discovering a new cardiac arrhythmia mechanism in neonatal rat atrial monolayers using patterned illumination

POLYGON

LEDs

Tim De Coster, PhD

Pijnappels Lab, Leiden University Medical Center


Exploration of the mechanism of refractive error in the mouse retina

POLYGON

So Chung Him, PhD

Feng Lab, The Hong Kong Polytechnic University


Interleaved complementary dual-λ photo-stimulation facilitates high spatial-temporal precision labeling

POLYGON

Xinyu Xie

Yu Lab, Sichuan University


Induction of CA1 Theta-Nested Gamma Oscillations Using Layer-Specific Optogenetic Stimulation

POLYGON

James L. Butler, PhD

Paulsen Lab, University of Cambridge


A rostro-caudal map of V1 inhibition in axial motor circuits

POLYGON

Mohini Sengupta, PhD

Bagnall Lab, Washington University in St Louis


Photopatterning of multi-domain DNA hydrogels

POLYGON

Misha Rubanov, PhD

BSchulman Lab, Johns Hopkins University


Pixelated wrinkles using patterned optical phase retardation

POLYGON

Kitae Kim, PhD

Na Lab, Chungnam National University


Examining functional connectivity within the cerebellar microcircuit

POLYGON

Kim Gruver, PhD

Watt Lab, McGill University


Photopatterning with mercaptopropylsilatrane and the Polygon 1000

POLYGON

Mark Mitmoen, PhD

Kedem Lab, Marquette University


Protein Phase Separation Provides Long-Term Memory of Transient Spatial Stimuli

POLYGON

Elliot Dine, PhD

Toettcher Lab, Princeton University


In vivo calcium imaging of somatostatin-expressing cell activity in the cingulate cortex during social interaction in freely moving mice using Mightex’s OASIS Fiberscope

OASIS Fiberscope

Huanhuan Li, PhD

Lau Lab, The City University of Hong Kong


Visualizing Vimentin Filament Dynamics Using Photoconversion with the Mightex Polygon

POLYGON

Bhuvanasundar Renganathan

Gelfand Lab, Northwestern University


Short-term plasticity in hippocampal CA1 synapses for different presynaptic activity patterns – Effect of in vivo-like background activity on long-term synaptic plasticity

POLYGON

LEDs

Sulu Mohan

National Centre for Biological Sciences, India


Demonstration of Single-Cell Optical Control with the Polygon Pattern Illuminator

POLYGON

Matthew Tran Headshot

Matthew Tran, PhD

Richards Lab, University of Toronto


Perceptual Invariance to the Olfactory Spatio-Temporal Code

POLYGON

Edmund Chong Headshot

Edmund Chong

Rinberg Lab, New York University


Photopharmacology: New Tools for Optical Control in Biology and Medicine

LEDs

Andrew Woolley, PhD

Department of Chemistry, University of Toronto


Simultaneous Optogenetic Stimulation and Electrophysiology Recordings

Polygon

Matthew Tran Headshot

Matthew Tran, PhD

Richards Lab, University of Toronto


Mushroom body output neurons MBON-a1/a2 define an odor intensity channel that regulates behavioral odor discrimination learning in larval Drosophil

POLYGON

Abdulkadir Mohamed

Masuda-Nakagawa Lab, University of Cambridge


Upstream mobility and swarming of light activated micromotors

POLYGON

Binzhu Wu

Das Lab, University of Delaware


Social memory deficit caused by dysregulation of the cerebellar vermis

OASIS Fiberscope

O.Y. Chao, PhD

Yang Lab, University of Minnesota Medical School


High depth spatial transcriptome analysis by photo isolation chemistry

POLYGON

Mizuki Honda, PhD

Ohkawa Lab. Kyushu University


Silencing CCK-expressing ACC projections in the iPAG blocks social enhancement of pain

OASIS Fiberscope

Sandra Poulson

Martin Lab. University of Toronto


An optogenetic toolkit for light-inducible antibiotic resistance

POLYGON

Michael B. Sheets

Dunplop Lab, Boston University


All-optical interrogation of millimeter-scale networks and application to developing ferret cortex

POLYGON

Haleigh N. Mulholland

Smith Lab, University of Minnesota


Targeted micro-fiber arrays for measuring and manipulating localized multi-scale neural dynamics over large, deep brain volumes during behavior

POLYGON

Mai-Anh T. Vu, PhD

Howe Lab, Boston University


Restoration of visual function and cortical connectivity after ischemic injury through NeuroD1-mediated gene therapy

POLYGON

Yu Tang, PhD

Chubykin Lab, Purdue University


Neuronal sensorimotor integration guiding salt concentration navigation in Caenorhabditis

POLYGON

Ayaka Matsumoto

Lino Lab, University of Tokyo


Light-directed in situ barcoding of biomolecules in fixed cells and tissues for spatially indexed sequencing

POLYGON

Jocelyn Y. Kishi, PhD

Yin Lab, Harvard Medical School


Serotonergic modulation of vigilance states in zebrafish and mice

POLYGON

Yang Zhao

Song Lab, Tongii University


Elucidating dynamic intracellular signalling pathways of hippocampus-dependent memory with the OASIS Fiberscope

OASIS Fiberscope

Jayant Rai

Okamoto-Zhen Lab, University of Toronto


Spatiotemporal control of inflammatory lytic cell death through optogenetic induction of RIPK3 oligomerization

POLYGON

Teak-Jung Oh

Zhang Lab, University of Illinois


Synergism between two BLA-to-BNST pathways for appropriate expression of anxiety-like behaviors in male mice

POLYGON

Ren-Wen Han

Pan Lab, Nanchang University


Rapid and reversible dissolution of biomolecular condensates using light-controlled recruitment of a solubility tag

POLYGON

Ellen Brumbaugh-Reed

Toettcher Lab, Princeton University


Daily oscillations of neuronal membrane capacitance

POLYGON

Daniel Severin

Golowasch Lab, New Jersey Institute of Technology


Self-organization of modular activity in immature cortical networks

POLYGON

Haleigh N. Mulhollannd

Smith Lab, University of Minnesota


Revealing single-neuron and network-activity interaction by combining high-density microelectrode array and optogenetics

POLYGON

Toki Kobayashi

Jimbo Lab, University of Tokyo


Light-sensitive Ca2+ signaling in the mammalian choroid

POLYGON

Ahmed M. Eltanahy, PhD

Gonzales Lab, University of Nevada


Effective Regulation of Auditory Processing by Parvalbumin Interneurons in the Tail of the Striatum

POLYGON

Xuan Li

Liang Lab, Southern Medical University


Precise control of intracellular trafficking and receptor‐mediated endocytosis in living cells and behaving animals

POLYGON

Shiau-Chi Chen

Lin Lab, National Tsing Hua University


ERK synchronizes embryonic cleavages in Drosophila

POLYGON

Liu Yang

Shvartsman Lab, Princeton University


Bright and photostable yellow fluorescent protiens for extended imaging

POLYGON

Jihwan Lee

St-Pierre Lab, Baylor College of Medicine


Photocaged L-lactate and enhanced fluorescent imaging

POLYGON

Jihwan Lee

Rice University