What Do You Need to Perform In Vivo Calcium Imaging?
If someone were to describe in vivo calcium imaging to you, it might sound quite simple. When you dig deeper, you start to appreciate the complexity associated with the biology and equipment [...]
What is In Vivo Calcium Imaging?
The brain contains over a billion neurons, each with complex networks of connections. Patterns of neural activity are believed to generate specific aspects of behaviour and cognition, but how can [...]
What’s Happening at SFN 2019?
SFN 2019 in Chicago is approaching fast! Of course, there are lots of great talks and posters related to imaging and optogenetics. You can find Mightex at booth 1755 at SFN 2019 with equipment [...]
Congrats to CAN Travel Grant Winners: Kim Gruver & Azam Asgarihafshejani
Congratulations to our CAN 2019 Travel Grant winners Kim Gruver (McGill University) from Dr. Alanna Watt’s lab and Azam Asgarihafshejani (Universite de Montreal) from Dr. Jean-Claude [...]
How It Works: Decoding Network Activity in the Prefrontal Cortex with Single-Cell Resolution Optogenetics
Working memory enables us to both temporarily hold information in our minds for further cognitive processing and direct future behaviour. Previous studies in rodents demonstrate that subsets of [...]
Introducing the Polygon1000 Pattern Illuminator
Mightex is proud to introduce the next generation of Polygon for patterned illumination, the Polygon1000. The Polygon1000 provides the same features and reliability as Mightex’s market-leading [...]
How It Works: Grid-Scanning Optogenetic Stimulation to Study Plasticity in Cortical Neurons
The ability to change the strength of connections between neurons, known as synaptic plasticity, has been shown to be extremely important for learning and memory within the brain. One proposed [...]
Come Visit Mightex at SFN 2018 in San Diego, California (Booth #3130)!
SFN 2018 (November 11-14th) in San Diego, California is approaching fast and Mightex will be attending (booth #3130). Mightex will have live demos of their Polygon400 patterned illuminator for [...]
Congrats to Travel Grant Winner: Matthew Tran from the University of Toronto!
Congratulations to our recent Travel Grant winner Matthew Tran (University of Toronto) from Dr. Blake Richard’s lab! Matthew presented his research using the Polygon400 this year at FENS [...]
How It Works: Patterned illumination to Study Protein Phase Separation in Living Cells with Optogenetics
Asymmetric distribution of determinants is an important mechanism for patterning cells and embryos throughout development. Whether it is the polarized localization of PAR proteins, or RNA and [...]