When selecting an optogenetic light source, you need to consider two key factors: the required light wavelength and intensity. First, the opsin you select has a specific activation spectrum, such [...]
Selective Optogenetic Stimulation with MEA to Detect Spread – Papasavvas et al. 2020 eNeuro Interneurons are directly connected by gap junctions to other interneurons, and this provides a [...]
Targeted Illumination in Zebrafish – Tabor et al. 2018 Current Biology Tabor et al. 2018 examined the cellular-basis of sensory filtering in zebrafish using prepulse inhibition (PPI). PPI [...]
The ability to illuminate select neurons within a population of optogenetic-expressing neurons is called cellular-resolution optogenetics (Shemesh et al. 2017). To use this technique, researchers [...]
Patterned illumination technologies enable researchers to selectively illuminate parts of their sample for optogenetic stimulation. One application of this is cellular-resolution optogenetics: [...]
Optogenetics is a technique to manipulate genetically-defined neural activity with light, and it has two main advantages: Millisecond Temporal Precision Genetically-Defined Spatial Precision [...]
Optogenetics unlocks the ability to activate or inhibit select populations of neurons. With this technique, researchers have been able to investigate the causal relationship between neural [...]
For years, neuroscientists have been fixated on understanding how behavior and cognition arise from neural circuit activity. To begin investigating these questions, scientists have been employing [...]
The invention of optogenetics has enabled scientists to use light to turn cell-type specific neural activity on or off with millisecond-precision to probe neural circuit function. Complementing [...]
A long-standing objective in neuroscience has been elucidating how in vivo neural activity relates to sensory processing, behaviour, cognition, and cortical processing. Researchers have attempted [...]
