With Sub-Cellular Resolution
Photostimulation:
Cell Biology Optogenetics
Overview

Optogenetic toolkits have expanded to offer cell biologists unprecedented spatiotemporal molecular and cellular control. From cell migration to gene regulation or developmental processes, cell biologists now have the ability to elicit specific biological responses with an incredible amount of precision in specific cells within organisms or subcellular regions of individual cells using optogenetics. Specifically, researchers are able to use the methodology depicted below to investigate multiple spatiotemporal biological responses.

single-colour optogenetics cell biology
dual-colour optogenetics cell biology

Key Requirements

sub-cellular resolution to stimulate small regions within cells
multi-colour stimulate any optogenetic probe
complimentary patterns stimulate multiple ROIs with different wavelengths
synchronization with imaging equipment and cameras

System Configurations

(Click below to view the relevant system configuration)

(1) Single-Colour Optogenetics

single_inverted2

This configuration based on Mightex’s Polygon400 provides:

1) Single-colour (e.g.CRY2) sub-cell resolution optogenetics of any optogenetic probe.

2) Synchronization with imaging equipment and camera.

3) Integrates into any commercial microscope (inverted or upright).

Components: (1) Polygon400, (2) Microscope Adapter, (3) Any Light Source, (4) Light Source Controller(s), & (5) Any Third-Party Camera.

(2) Dual-Colour Optogenetics

dual_inverted2

This configuration based on Mightex’s Polygon400 provides:

1) Dual-colour (e.g. PHYB/PIF, Dronpa) sub-cell resolution optogenetics of any optogenetic probe.

2) Stimulate independent regions with different colours.

3) Synchronization with imaging equipment and camera.

4) Integrates into any commercial microscope  (inverted or upright).

Components: (1) Polygon400 x2, (2) Microscope Adapter, (3) Any Light Source, (4) Light Source Controller(s), & (5) Any Third-Party Camera.

Main Component

polygon400 sub-cellular resolution optogenetics

Additional Components

microscope adapter
light sources
light source controllers
camera
Inquiry

Cell Biology Optogenetics Inquiry

Mightex will only use your personal information to provide the products and services you have requested. Please see our Privacy Policy for further details.