Issue 18, 2020
From the journal:

Analyst

Convection-driven microfabricated hydrogels for rapid biosensing†

Cheng Cheng,a   Mark H. Harpstera  and  John Oakey ORCID logo *a  

* Corresponding authors

a Department of Chemical Engineering, University of Wyoming, Laramie, WY 82070, USA
E-mail: joakey@uwyo.edu

Abstract

A microscale biosensing platform using rehydration-mediated swelling of bio-functionalized hydrogel structures and rapid target analyte capture is described. Induced convective flow mitigates diffusion limited incubation times, enabling model assays to be completed in under three minutes. Assay design parameters have been evaluated, revealing fabrication criteria required to tune detection sensitivity.

Graphical abstract: Convection-driven microfabricated hydrogels for rapid biosensing

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Article information

DOI
https://doi.org/10.1039/D0AN01069C
Article type
Communication
Submitted
27 May 2020
Accepted
13 Aug 2020
First published
14 Aug 2020

Analyst, 2020,145, 5981-5988

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Convection-driven microfabricated hydrogels for rapid biosensing

C. Cheng, M. H. Harpster and J. Oakey, Analyst, 2020, 145, 5981 DOI: 10.1039/D0AN01069C

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