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Blog

Research Focus: An optogenetic toolkit for light-inducible antibiotic resistance (Sheets et al., 2023)
Check out this recent publication using the Polygon 1000! The paper outlines research by Michael B. sheets, Nathan Tague, and Mary J. Dunlop from Boston University using the Polygon to develop an optogenetic toolbox for inducing antibiotic resistance using 463nm light. We are excited to see more to come using...
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Research Focus- Light-Seq: light-directed in situ barcoding of biomolecules in fixed cells and tissues for spatially indexed sequencing
Check out this recent publication using the Polygon 1000! The paper outlines research by Jocelyn Kishi, Ninning Liu, Emma R. West, and colleagues from Harvard University using the Polygon for UV photocross-linking for a novel method of DNA barcoding. We are excited to see more to come using the LightSeq...
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In-vitro Seizure Suppression by Patterned Optogenetic Stimulation while Allowing Information Processing in Hippocampus
Md Joynal Abedin is a postdoctoral scholar in the Berdichevsky Lab at LeHigh University and a recipient of a Mightex 2022 Travel Award. The work outlined above was presented at the 2022 Society for Neuroscience conference in San Diego, November, 2022. Content courtesy of Md Joynal Abedin.
Most prevalent refractory...
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Mightex Award Winner II: Zubayer Ibne Ferdous (LeHigh University)
We are pleased to share the recent work of Zubayer Ibne Ferdous, a doctoral student in the Berdichevsky Lab at LeHigh University and a recent recipient of the Mightex Travel Award for their work using the Mightex Polygon for patterned optogenetics examination of neural computation in cortical...
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Mightex Travel Award Winner I: Md Joynal Abedin (LeHigh University)
We are pleased to share the recent work of Md. Joynal Abedin, a postdoctoral researcher in the Berdichevsky Lab at LeHigh University, and a recent recipient of the Mightex Travel Award for their work using the Mightex Polygon for patterned optogenetics examination of seizure activity in slice...
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SfN and ASCB Highlights 2022
Our team have been busy meeting with our neuroscience and cell biology research communities at the Society for Neuroscience and American Cell Biology conferences this fall! Check out this blog post to learn more about their conference experiences and the Mightex products showcased at these conferences.
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OASIS Implant Publication Feature: Activation of Somatostatin-Expressing Neurons in the Lateral Septum Improves Stress-Induced Depressive-like Behaviors in Mice
Check out this recent publication using the OASIS Implant! The paper outlines research by Huanhuan Li and colleagues from Geoff Lau's lab at the City University of Hong Kong. The limbic system, including the lateral septum (LS), plays a crucial role in mood disorders, such as depression. However, the role of...
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Photopatterning with mercaptopropylsilatrane (MPS) and the Polygon 1000
Check out this Polygon 1000 customer highlight focused on Mark Mittmoen. Mark is a doctoral student in Dr. Ofer Kedem's lab at Marquette University. He uses UV and visible light with the Polygon 1000 to create highly complex photopatterns. Mark recently published his work on this topic in ACS Applied...
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In vivo calcium imaging of somatostatin positive neurons during social interaction tasks
Check out this OASIS Implant customer highlight focused on Huanhuan Li. Huanhuan spoke with Mightex Applications Scientist, Dr Catherine Thomas, about his doctoral work using the OASIS Implant to conduct in vivo Ca2+ imaging of somatostatin-expressing cell activity in the cingulate cortex during social interaction test in freely moving mice.
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Examining functional connectivity within the cerebellar microcircuit
We are pleased to share recent work from Kim Gruver, a recipient of the Mightex Annual Research Award, 2021, and Mightex Student Travel Award for presetnign her work at the Canadian Association for Neuroscience (CAN) meeting in Toronto (May, 2022). Kim's doctoral work combines patterned illumination from the Mightex Polygon...
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The Mightex Team at Summer Conferences 2022
Our frontline team have been busy connecting with our scientific communities across numerous research fields including behavioural neuroscience, microfluidics, and nanorobotics. The team provided live demonstrations of our Polygon and OASIS Implant systems showcasing their market-leading capabilities to conference attendees. Thank you to all of the conference organizers and attendees...
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Investigating Signalling Pathways in Hippocampus-Dependent Memory with the OASIS Implant
We are pleased to share recent work from the first prize recipient of the Mightex Annual Research Award, 2021, Jayant Rai. Jay spoke with Mightex Applications Scientist Dr Catherine Thomas about his doctoral work using the OASIS Implant to investigate intracellular signalling pathways involved in hippocampus-dependent memory.
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Md Joynal Abedin is a postdoctoral scholar in the Berdichevsky Lab at LeHigh University and a recipient of a Mightex 2022 Travel Award. The work outlined above was presented at the 2022 Society for Neuroscience conference in San Diego, November, 2022. Content courtesy of Md Joynal Abedin.

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