The OASIS Photometry System is a versatile, high-throughput fiber photometry system designed to simultaneously record neural activity across multiple animals and regions of interest. Combining high-speed, multi-wavelength fluorescence imaging with precise synchronization of behavioural events and experimental hardware, OASIS enables researchers to capture multiple fluorescent indicators, integrate optogenetic stimulation, and efficiently generate reproducible data for advanced in vivo neuroscience and behavioural research.